发明名称 USE OF INDOLOQUINOXALINE DERIVATIVES FOR PREPARING A DRUG FOR THE TREATMENT OF MULTIPLE SCLEROSIS
摘要 Use of a compound of formula (I) wherein R1 represents hydrogen or one or several, preferably 1 to 4, similar or different substituents in the positions 1-4 and/or 7-10, selected from halogen, preferably Br, lower alkyl/alkoxy group having not more than 4 carbon atoms, trifluoromethyl group, trichloromethyl group; and in one of the positions 7-10 R1 can be a hydroxyl group; X is a group -(CH2)n-R2, wherein R2 represents a nitrogen containing basic residue such as NH2, NHR4 or NR5R6, wherein R4, R5 and R6 independently are lower alkyl or cycloalkyl and n is an integer of from 1 to 4 and R3 represents hydrogen, lower alkyl/cycloalkyl group having not more than 4 carbon atoms, and the physiologically acceptabl e addition products of the compounds with acids and halogen adducts, preferably adducts with iodine, iodine monochloride or iodi ne monobromide, for preparing a drug for treatment of MS (multiple sclerosis).
申请公布号 CA2400236(C) 申请公布日期 2009.09.22
申请号 CA20012400236 申请日期 2001.02.16
申请人 LUNDBLAD, LEIF J.I. 发明人 MOLLER, LENNART;BERGMAN, JAN
分类号 A61K31/519;C07D487/04;A61K31/4985;A61P25/00;A61P25/28 主分类号 A61K31/519
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