发明名称 COMBINATORIAL THERAPY
摘要 The present invention relates to the use of VEGF antagonists and alpha5beta1 antagonists for treating cancer and inhibiting angiogenesis and/or vascular permeability, including inhibiting abnormal angiogenesis in diseases. The present invention also relates to use of a VEGFR agonists and alpha5beta1 agonists to promote angiogenesis and vascular permeability. The present invention also relates to new anti-alpha5beta1 antibodies, compositions and kits comprising them and methods of making and using them.
申请公布号 US2009220504(A1) 申请公布日期 2009.09.03
申请号 US20070293382 申请日期 2007.03.21
申请人 发明人 CHUNTHARAPAI ANAN;PLOWMAN GREGORY D.;TESSIER-LAVIGNE MARC;WU YAN;YE WEILAN
分类号 A61K39/395;A61P27/02;A61P35/00;A61P37/00;C07H21/00;C07K16/28;C12N5/00;C12N15/63;G01N33/53 主分类号 A61K39/395
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