| 发明名称 |
Substituted Amino-Compounds and Uses Thereof |
| 摘要 |
This invention relates to novel compounds having the structural formula Ia or formula Ib: Ia Ib and their pharmaceutically acceptable salts, tautomers or in vivo hydrolysable precursors, compositions and methods of use thereof. These novel compounds provide a treatment or prophylaxis of Abeta related pathologies such as cognitive impairment, Alzheimer Disease, neurodegeneration and dementia.
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| 申请公布号 |
US2009221579(A1) |
申请公布日期 |
2009.09.03 |
| 申请号 |
US20050577155 |
申请日期 |
2005.10.14 |
| 申请人 |
ALBERT JEFFREY SCOTT;ANDISIK DON;ARNOLD JAMES;BROWN DEAN;CALLAGHAN OWEN;CAMPBELL JAMES;CARR ROBIN ARTHUR ELLIS;CHESSARI GIANNI;CONGREVE MILES STUART;EDWARDS PHIL;EMPFIELD JAMES R;FREDERICKSON MARTYN;KOETHER GERARD M;KRUMRINE JENNIFER;MAUGER RUSS;MURRAY CHRISTOPHER WILLIAM;PATEL SAHIL;SYLVESTER MARK;THRONER SCOTT |
发明人 |
ALBERT JEFFREY SCOTT;ANDISIK DON;ARNOLD JAMES;BROWN DEAN;CALLAGHAN OWEN;CAMPBELL JAMES;CARR ROBIN ARTHUR ELLIS;CHESSARI GIANNI;CONGREVE MILES STUART;EDWARDS PHIL;EMPFIELD JAMES R.;FREDERICKSON MARTYN;KOETHER GERARD M.;KRUMRINE JENNIFER;MAUGER RUSS;MURRAY CHRISTOPHER WILLIAM;PATEL SAHIL;SYLVESTER MARK;THRONER SCOTT |
| 分类号 |
A61K31/5377;A61K31/513;A61P25/28;C07D239/47;C07D413/10;C12N9/99 |
主分类号 |
A61K31/5377 |
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