发明名称 |
SOLID-STATE SALT ARGATROBAN FORMULATIONS AND METHODS FOR PRODUCING AND USING THE SAME |
摘要 |
Argatroban formulations and methods of making and using the formulations are provided. In an embodiment, the present disclosure provides a solid-state salt formulation of argatroban. Upon reconstitution, the solid-state argatroban forms a solution that can be essentially free of particles and suitable for administration. The solid-state argatroban can be in a crystalline and/or amorphous form. The solid-state argatroban can be packaged in a sealed container that may be aseptically-filled to reduce the microbiological burden of the formulation. The solid-state argatroban can be reconstituted with a solution and administered to persons needing same.
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申请公布号 |
US2009221637(A1) |
申请公布日期 |
2009.09.03 |
申请号 |
US20080040768 |
申请日期 |
2008.02.29 |
申请人 |
BAXTER INTERNATIONAL INC.;BAXTER HEALTHCARE S.A. |
发明人 |
OWOO GEORGE |
分类号 |
A61K31/4709;A61L33/04;A61P7/02 |
主分类号 |
A61K31/4709 |
代理机构 |
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主权项 |
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