摘要 |
<p>Disclosed is a medicated patch comprising a medicinal agent, an adhesive base material and an adhesiveness-imparting agent, wherein the medicinal agent is varenicline or a pharmaceutically acceptable salt thereof, the adhesive base material is a rubbery adhesive base material, and the adhesiveness-imparting agent is an rosin-type adhesiveness-imparting agent selected from the group consisting of rosin, a rosin derivative and a hydrogenated product of rosin or the rosin derivative or a non-rosin-type adhesiveness-imparting agent selected from the group consisting of an aliphatic hydrocarbon resin and an alicyclic hydrocarbon resin. When a non-rosin-type adhesiveness-imparting agent is used as the adhesiveness-imparting agent, the medicated patch further contains a solubilizer for the medicinal agent, wherein the solubilizer comprises an alcohol-type solubilizer having at least a solubility parameter of 20 to 35.</p> |
申请人 |
HISAMITSU PHARMACEUTICAL CO., INC.;YAMAMOTO, NAOKI;MORIMOTO, KUMI;TAKEUCHI, AKIO;ISHIGAKI, KENJI |
发明人 |
YAMAMOTO, NAOKI;MORIMOTO, KUMI;TAKEUCHI, AKIO;ISHIGAKI, KENJI |