发明名称 NOVEL COMPOSITION AND METHOD IN CANCER ASSOCIATED WITH ALTERED EXPRESSION OF PRDM 11
摘要 <P>PROBLEM TO BE SOLVED: To provide a sequence related to cancer (especially carcinogenesis and breast cancer). <P>SOLUTION: Provided is a novel sequence related for use in the diagnosis and treatment of carcinomas (especially breast cancers). In addition, described is the use of novel compositions for use in screening methods. Provided are compositions and methods in cancer associated with altered expression of PRDM11. Provided is a method for screening a medicine candidate. The method includes the processes of: (a) a process for providing a cell which contains a nucleic acid sequence selected from the group consisting of specific sequence and its fragments and expresses a cancer-associated (CA) gene; (b) a process for adding the medicine candidate to the cell, and (c) a process for determining the effect of the medicine candidate in the expression of the CA gene. <P>COPYRIGHT: (C)2009,JPO&INPIT
申请公布号 JP2009195242(A) 申请公布日期 2009.09.03
申请号 JP20090107166 申请日期 2009.04.24
申请人 SAGRES DISCOVERY INC 发明人 MORRIS DAVID W
分类号 C12N15/09;A61K31/7088;A61K38/00;A61K39/395;A61K45/00;A61K48/00;A61P15/00;A61P35/00;A61P35/02;C07K14/47;C07K14/82;C07K16/18;C07K16/32;C12M1/00;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12Q1/02;C12Q1/68;G01N33/15;G01N33/50;G01N33/53;G01N33/566;G01N33/574 主分类号 C12N15/09
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