发明名称 |
Sucralose Formulations To Mask Unpleasant Tastes |
摘要 |
The present invention is directed to a pharmaceutically acceptable taste masking liquid excipient base for administration of a relatively large amount of unpleasant tasting medicines. More particularly, the enhanced sweetness and taste masking effect are produced by the addition of sucralose to the excipient base with maintenance of a pH from about 2 to about 5. The invention is further directed to medicinal compositions comprising such a liquid excipient base and unpleasant tasting medicines. Still further, the invention is directed to a method for taste masking unpleasant tasting medicines through their incorporation into the claimed liquid excipient bases.
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申请公布号 |
US2011136851(A1) |
申请公布日期 |
2011.06.09 |
申请号 |
US201113018932 |
申请日期 |
2011.02.01 |
申请人 |
WYETH LLC |
发明人 |
JAEGER DAVID;DICKERSON JAY;TRIMMER ANNABELLE |
分类号 |
A61K31/485;A61K47/36;A61K9/00;A61K31/09;A61K31/137;A61K31/167;A61K31/192;A61K31/4402;A61K45/00;A61K47/26;A61P11/02;A61P11/10;A61P11/14;A61P29/00 |
主分类号 |
A61K31/485 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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