MINIMUM TIME FEEDBACK CONTROL OF EFFICACY AND SAFETY OF THERMAL THERAPIES

摘要

A thermal treatment control system including an imaging device for specifying the geometry and/or location of the treatment target, a thermal energy element for applying a thermal treatment for the heating or cooling of a target tissue for therapeutic purposes, a thermal energy detecting element for detecting a measured tissue response to the thermal treatment and a feedback controller for a real-time modification of the intensity and spatial distribution of the thermal dose in order to achieve therapeutic efficacy over a minimum or reduced treatment time while satisfying treatment constraints imposed to limit damage to normal tissues.