THERAPIES FOR PREVENTING OR SUPPRESSING CLOSTRIDIUM DIFFICILE INFECTION
摘要
The present invention provides an antibody composition comprising ovine antibodies, for use in the prevention or treatment of C. difficile infection wherein the antibodies bind to a C. difficile toxin, and wherein said prevention or treatment is by oral delivery of the antibody composition. Also provided is a pharmaceutical composition of ovine antibodies for oral delivery, which further comprises one or more means for protecting the antibodies from trypsin and/ or chymotrypsin and/ or stomach acid.
申请公布号
WO2011067616(A1)
申请公布日期
2011.06.09
申请号
WO2010GB52035
申请日期
2010.12.06
申请人
HEALTH PROTECTION AGENCY;MICROPHARM LIMITED;SHONE, CLIFFORD;ROBERTS, APRIL;LANDON, JOHN