摘要 |
<p>Acid-addition salts of cpds. of formula : (where R1 is H, Cl, Br, F or alkyl; R2 is CN, COOR5 or CONR5R6; R3 is H or alkyl; R4 is H or alkyl; R5 is H or alkyl; R6 is H or alkyl; in CONR5R6, R5 and R6 may form a 5- or 6-membered ring; n is 0-3) are prepd. by treating a 5-hydroxy-1,3,4,4a,5,9b-hexahydroindeno-1,2-c/-pyridine with Hal-CHR3-CHR4-/CH2/n-R2 (where Hal is Cl, Br or I) in the presence of base, and then dehydrating the product with a strong acid or acid halide. The products are antiphlogistic, anti-ulcerous, hypotensive and anorexigenic agents.</p> |