| 发明名称 |
EYA2S As Modifiers of the PTEN/AKT Pathway and Methods of Use |
| 摘要 |
Human MPTENAKT genes are identified as modulators of the PTEN/AKT pathway, and thus are therapeutic targets for disorders associated with defective PTEN/AKT function. Methods for identifying modulators of PTEN/AKT, comprising screening for agents that modulate the activity of MPTENAKT are provided.
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| 申请公布号 |
US2011135629(A1) |
申请公布日期 |
2011.06.09 |
| 申请号 |
US20060993130 |
申请日期 |
2006.06.20 |
| 申请人 |
EXELIXIS, INC. |
发明人 |
BRACE ARTHUR;BJERKE MARGARET LYNN;NIETO-BERGMAN SUSANA;FRIEDMAN LORI S.;WARD KEVIN;BLAKE ROBERT A. |
| 分类号 |
A61K39/395;A61K31/7088;A61P35/00;C12N5/00;C12Q1/48;C12Q1/68;G01N33/53 |
主分类号 |
A61K39/395 |
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