TRANSGENIC ANIMAL MODEL OF CANCER AND METHODS OF USE
摘要
The invention features a transgenic mouse model of cancer, exemplified by basal cell carcinoma, which finds use in identification of anti-cancer drugs. The transgenic mouse is characterized by a heterozygous defect in a Patch gene (Ptch+/-) and an inducible suppression of functional p53.
申请公布号
WO2009126808(A3)
申请公布日期
2011.06.09
申请号
WO2009US40072
申请日期
2009.04.09
申请人
CHILDREN'S HOSPITAL & RESEARCH CENTER AT OAKLAND;EPSTEIN, ERVIN, H.;SO, PO-LIN;TANG, JEAN