METHODS FOR DETECTING DIHYDROXYVITAMIN D METABOLITES BY MASS SPECTROMETRY
摘要
<p>Provided are methods of detecting the presence or amount of a dihydroxyvitamin D metabolite in a sample using mass spectrometry. The methods generally comprise ionizing a dihydorxyvitamin D metabolite in a sample and detecting the amount of the ion to determine the presence or amount of the vitamin D metabolite in the sample. In certain preferred embodiments the methods include immunopurifying the dihydroxyvitamin D metabolites prior to mass spectrometry. Also provided are methods to detect the presence or amount of two or more dihydroxyvitamin D metabolites in a single assay.</p>
申请公布号
WO2011068673(A1)
申请公布日期
2011.06.09
申请号
WO2010US56886
申请日期
2010.11.16
申请人
QUEST DIAGNOSTICS INVESTMENTS INCORPORATED;HOLMQUIST, BRETT;CLARKE, NIGEL J.