发明名称 CASPASE INHIBITOR PRODRUGS
摘要 This invention relates to prodrugs of caspase inhibitors comprising of a furo[3,2-d]oxazolin-5-one moiety which, under specific conditions, can convert into biologically active compounds, particularly caspase inhibitors. This invention also relates to the processes for preparing these prodrugs of caspase inhibitors. This invention further relates to pharmaceutical compositions comprising said prodrugs and to the use thereof for the treatment of diseases related to inflammatory or degenerative conditions.
申请公布号 US2011137037(A1) 申请公布日期 2011.06.09
申请号 US20100971649 申请日期 2010.12.17
申请人 VERTEX PHARMACEUTICALS INCORPORATED 发明人 DURRANT STEVEN;CHARRIER JEAN-DAMIEN;STUDLEY JOHN
分类号 C07D498/04 主分类号 C07D498/04
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