发明名称 POLYMORPHS OF A MEK INHIBITOR
摘要 The present invention relates to polymorphic forms of 7-(4-Bromo-2-fluoro-phenylamino)-6-methyl-5-oxo-1,3,5-tetrahydro-indolizine-8-carboxylic acid (2-hydroxy-ethoxy)-amide and a hydrate thereof which are useful in the treatment of a disease, disorder or syndrome associated with MEK inhibition, such as cancer, in mammals. The invention also relates to compositions thereof and to methods of using such compositions in the treatment of cancer in mammals, especially humans.
申请公布号 WO2011067356(A2) 申请公布日期 2011.06.09
申请号 WO2010EP68776 申请日期 2010.12.02
申请人 NOVARTIS AG;WAYKOLE, LILADHAR, MURLIDHAR;KARPINSKI, PIOTR, H.;XUE, SONG;BELTZ, KAREN;SEILER, FRANK HANS 发明人 WAYKOLE, LILADHAR, MURLIDHAR;KARPINSKI, PIOTR, H.;XUE, SONG;BELTZ, KAREN;SEILER, FRANK HANS
分类号 C07D471/04 主分类号 C07D471/04
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