| 发明名称 |
METHODS TO DIAGNOSE AND IMMUNIZE AGAINST THE VIRUS CAUSING HUMAN MERKEL CELL CARCINOMA |
| 摘要 |
The present invention provides isolated or substantially purified polypeptides, nucleic acids, and virus-like particles (VLPs) derived from a Merkel cell carcinoma virus (MCV), which is a newly-discovered virus. The invention further provides monoclonal antibody molecules that bind to MCV polypeptides. The invention further provides diagnostic, prophylactic, and therapeutic methods relating to the identification, prevention, and treatment of MCV-related diseases. |
| 申请公布号 |
US2011135598(A1) |
申请公布日期 |
2011.06.09 |
| 申请号 |
US20080808042 |
申请日期 |
2008.12.15 |
| 申请人 |
UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION;THE U.S.OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES |
发明人 |
MOORE PATRICK M.;CHANG YUAN;FENG HUICHEN;BUCK CHRISTOPHER BRIAN;PASTRANA DIANA V. |
| 分类号 |
A61K39/275;A61K31/436;A61K31/675;A61K31/7076;A61K31/7088;A61K35/12;A61K38/16;A61K38/21;A61P31/20;A61P35/00;A61P37/04;C07H21/00;C07K14/065;C07K16/08;C12N15/63;C12Q1/68;C12Q1/70;C40B40/10 |
主分类号 |
A61K39/275 |
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