发明名称 |
MELANOMA ASSOCIATED PEPTIDE ANALOGUES AND VACCINES AGAINST MELANOMA |
摘要 |
The present invention is concerned with cancer treatment and diagnosis, especially with melanoma associated peptide analogues with improved immunogenicity, epitopes thereof; vaccines against melanoma, tumor infiltrating T lymphocytes recognizing the antigen and diagnostics for the detection of melanoma and for the monitoring of vaccination. The peptides according to the invention can be exploited to elicit native epitope-reactive Cm. Usage of the peptides with improved immunogenicity may contribute to the development of CTL-epitope based vaccines in viral disease and cancer.
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申请公布号 |
US2011135675(A1) |
申请公布日期 |
2011.06.09 |
申请号 |
US20100961217 |
申请日期 |
2010.12.06 |
申请人 |
THE UNITED STATES OF AMERICA, AS REPRESENTED BY SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICE |
发明人 |
FIGDOR CARL GUSTAV;ADEMA GOSSE JAN |
分类号 |
A61K39/00;A61K38/00;A61K38/08;A61P37/04;C07K7/06;C07K14/47;C07K16/30;C12N5/00 |
主分类号 |
A61K39/00 |
代理机构 |
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主权项 |
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