发明名称 Localized Chemical Lysis of Ocular Tissue
摘要 A high-intensity pulsed-electrical-field (HIPEF) apparatus chemically induces lysis of ocular tissue within a localized portion of an eye. Instead of broadly applying a lysis affecting solution (e.g., plasmin) to the eye, the apparatus delivers solution to only a portion of the eye. The apparatus then alters the effectiveness of at least some of the solution delivered by applying a HIPEF to that solution. In some embodiments, for example, the apparatus delivers a solution that does not substantially affect lysis of ocular tissue and then enhances the solution's effectiveness by applying a HIPEF. As the apparatus applies the HIPEF with high precision, the HIPEF only enhances the effectiveness of the solution within select and localized portions of the eye. The apparatus is especially advantageous for vitreoretinal surgery, whereby the apparatus may selectively induce lysis of vitreous tissue within a localized portion of the vitreous cavity, without significantly affecting adjacent retinal tissue.
申请公布号 US2011135626(A1) 申请公布日期 2011.06.09
申请号 US20090633473 申请日期 2009.12.08
申请人 ALCON RESEARCH, LTD. 发明人 KOVALCHECK STEVEN W.
分类号 A61K38/48;A61F9/007;A61P27/02 主分类号 A61K38/48
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