PROCESSES FOR SYNTHESIZING 1-(2-ETHYLBUTYL)CYCLOHEXANE CARBONITRILE

摘要

Processes are provided for synthesizing substituted cyclohexane carbonitriles, particularly 1-(2-ethylbutyl)cyclohexane carbonitrile. Such processes comprise deprotonizing cyclohexane carbonitrile with chloro magnesium N,N-diisopropylamide and alkylating the deprotonated cyclohexane carbonitrile in the presence of 2-(ethylbutyl) bromide to produce 1-(2-ethylbutyl)cyclohexane carbonitrile.