| 发明名称 |
DIAGNOSTIC AND THERAPEUTIC METHODS FOR CORNEAL ECTASIA FOLLOWING REFRACTIVE SURGERY, KERATOCONUS OR PELLUCID DEGENERATION |
| 摘要 |
<p>The present invention relates to methods of diagnosis and treatment of corneal ectasia following refractive surgery, keratoconus or pellucid marginal degeneration in a subject by determining or modulating the level of expression of molecules associated with the Wnt signalling pathway. Marker molecules of the present invention include SFRP1, PITX2, LEF1, WNT16 and WNT5A.</p> |
| 申请公布号 |
WO2011066621(A1) |
申请公布日期 |
2011.06.09 |
| 申请号 |
WO2010AU01633 |
申请日期 |
2010.12.02 |
| 申请人 |
THE UNIVERSITY OF SYDNEY;SUTTON, GERARD;MCEVOY, JOHN;MADIGAN, MICHELE |
发明人 |
SUTTON, GERARD;MCEVOY, JOHN;MADIGAN, MICHELE |
| 分类号 |
C12Q1/68 |
主分类号 |
C12Q1/68 |
| 代理机构 |
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