A COMPOSITION COMPRISING NOVEL FLAVONE DERIVATIVE FOR TREATING AND PREVENTING ATOPIC DERMATITIS DISEASE

摘要

PURPOSE: A sophoricoside derivative compound of isoflavone is provided to effectively suppress MCP-1, IL-6, and IL-8 and to prevent and treat atopic dermatitis. CONSTITUTION: A flavone derivative of novel straucture is denoted by general formula I. The flavone derivative compound is derived from Sophora japonica L. A pharmaceutical composition fore preventing and treating atopic dermatitis contains the flavone derivative compound and pharmaceutically acceptable salt thereof as an active ingredient. A health food for preventing and treating atopic dermatitis contains the flavone derivative compound or pharmaceutically acceptable salt thereof as an active ingredient. The health food is manufactured in the form of powder, granule, tablet, capsule, or beverage.