发明名称 |
METHOD OF DIAGNOSING OR PROGNOSING EPITHELIAL OVARIAN CANCER |
摘要 |
The present invention provides a binding moiety which selectively binds to Sox11 protein and/or mRNA for imaging, diagnosis or prognosis of epithelial ovarian cancer (EOC). Optionally, the moiety is an antibody or antigen binding fragment thereof. Advantageously, moiety comprises a further, readily detectable moiety. The invention also provides methods of imaging EOC cells as well as methods of diagnosing or prognosing EOC in an individual. A further aspect of the present invention provides a method of identifying cells associated with EOC, the method comprising analysing the pattern of gene expression in a sample of cells to be tested and comparing it to the pattern of gene expression in a sample of known lymphomas cells. |
申请公布号 |
EP2329042(A1) |
申请公布日期 |
2011.06.08 |
申请号 |
EP20090785026 |
申请日期 |
2009.09.01 |
申请人 |
IMMUNOVIA AB |
发明人 |
BORREBAECK, CARL, ARNE, KRISTER;EK, SARA, CHARLOTTE, ANDERSSON;BRENNAN, DONAL, JOHN |
分类号 |
C12Q1/68;G01N33/574 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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