METHODS OF TREATING COGNITIVE DISORDERS BY INHIBITION OF GPR12
摘要
The present invention provides methods for screening a pharmaceutical agent for its ability to modulate long term memory formation, performance of a hippocampal-dependent cognitive task or Gpr12 function. The present invention also provides methods for modulating long term memory formation or performance of a hippocampal-dependent cognitive task by modulating Gpr12-dependent protein expression. The present invention further provides methods for treating a defect in long term memory formation by inhibiting Gpr12 function and methods for treating a defect in performance of a hippocampal-dependent cognitive task by inhibiting Gpr12 function.
申请公布号
EP2162137(A4)
申请公布日期
2011.06.08
申请号
EP20080755619
申请日期
2008.05.15
申请人
HELICON THERAPEUTICS, INC.
发明人
PETERS, MARCO;SCOTT, RODERICK, E.M.;TULLY, TIMOTHY, P.