发明名称 COCRYSTALLINE FORM OF C-GLYCOSIDE DERIVATIVE WITH L-PROLIN
摘要 FIELD: medicine, pharmaceutics. ^ SUBSTANCE: this invention relates to cocrystalline form of (1S)-1,5-anhydro-1-[3-(1-benzothiene-2-ylmethyl)-4-fluorophenyl]-D-glucitol (compound A) with L-proline. Proposed cocrystalline form is a promising anti-diabetes medicine. ^ EFFECT: cocrystalline form of compound is characterised with constant composition, improved stability in storage, and also low hygroscopicity, and is suitable for use as crystalline medicinal substance to produce pharmaceutical preparations. ^ 11 cl, 1 ex, 2 tbl, 10 dwg
申请公布号 RU2408595(C2) 申请公布日期 2011.01.10
申请号 RU20080143362 申请日期 2007.04.04
申请人 ASTELLAS FARMA INK.;KOTOBUKI FARMAS'JUTIKAL KO., LTD. 发明人 IMAMURA MASAKAZU;NAKANISI KEJTA;SIRAKI RIOTA;ONDA KENITI;SASUGA DAJSUKE;JUDA MASAMITI
分类号 A61K31/381;A61P3/10;C07D407/10;C07D409/10 主分类号 A61K31/381
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