ANTI-INFLAMMATORY AND ANTINEOPLASTIC ANTICOAGULANT

摘要

FIELD: medicine, pharmaceutics. ^ SUBSTANCE: there is offered the administration of heparin conjugated with 2-aminoethanesulfonic acid (taurine) of formula (1), synthesised with a condensing reagent - water-soluble 1-ethyl-3[3 (dimethylamino)propyl]carbodiimide as an anti-inflammatory and antineoplastic anticoagulant. ^ EFFECT: compound surpasses heparin in anticoagulating ability, has high anti-inflammatory activity, while antineoplastic activity is comparable with the effect of antineoplastic preparations (doxorubicin, cyclophosphan, vincristine). ^ 5 tbl, 4 ex