AGENT FOR INCREASING RESERVED STEM CELL NUMBER IN ORGANISM

摘要

FIELD: medicine. ^ SUBSTANCE: invention refers to radiation synthesis nanotechnology for the creation of a low-immunogenicity agent to increase the reserved stem cell number in an organism, and can be used in regenerative medicine. The agent represents polymer immobilised hyaluronidase introduced in the dissolved low-molecular water-soluble polymer pre-exposed to ionising radiation in dosage 1-5 Mrad, to final concentration 70 UN in 1 ml. ^ EFFECT: invention allows producing immobilised hyaluronidase which is characterised by substantially higher ability to increase the reserved stem cell number in an organism and effective both in parenteral, and in oral introduction. ^ 4 tbl, 5 ex