MULTIPLE-SAMPLE MICROFLUIDIC CHIP FOR DNA ANALYSIS

摘要

Aspects of the disclosure provide a microfluidic chip. The microfluidic chip includes a first domain configured for polymerase chain reaction (PCR) amplification of DNA fragments, and a second domain for electrophoretic separation. The first domain includes at least a first reaction reservoir designated for PCR amplification based on a first sample, and a second reaction reservoir desginated for PCR amplification based on a second sample. The second domain includes at least a first seperation unit coupled to the first reaction reservoir to received first amplified DNA fragments based on the first sample, and a second serpataion unit coupled to the second reaction reservoir to received second amplified DNA fragments based on the second sample. The first separation unit is configured to perform electrophoretic separation for the first amplified DNA fragments, and the second separation unit is configured to perform electrophoretic separation for the second amplified DNA fragments.