N-PHENYL DICHLOROACETAMIDE AND THEIR DERIVATIVES, PREPARATION METHODS AND USES THEIROF

摘要

N-Phenyl dichloroacetamide and their derivatives which belong to pharmaceutical chemistry and organic synthesis fields are provided. These compounds have the structures of general formula I, in which N-{3-chloro-4-[(trifluoromethyl)sulfonyl]phenyl}dichloroacetamide is preferred. The preparation methods of these compounds are also provided, which are easy to conduct. There is no need to use any catalyst in these methods. Additionally, the uses of these compounds in the preparation of anticancer drugs which have high-effective and low toxic anticancer activities are provided.