发明名称 2-Amido-4-aryloxy-1-carbonylpyrrolidine derivatives as inhibitors of serine proteases, particularly HCV NS3-NS4A protease
摘要 Disclosed is an amino acid derivative including a pyrrolidine, of formula I, where the substituents and variables are as defined in the specification. Also disclosed is the use of the compound for inhibiting a serine protease, such as HCV NS3 protease. Also disclosed is the use of the compound to treat an HCV (hepatitis C virus) infection.
申请公布号 NZ580205(A) 申请公布日期 2011.04.29
申请号 NZ20040580205 申请日期 2004.09.07
申请人 VERTEX PHARMACEUTICALS INCORPORATED 发明人 PERNI, ROBERT B
分类号 A61K31/4178;A61K31/401;A61K31/4025;A61K31/4439;A61K31/497;A61K31/501;A61K31/506;A61K31/517;A61K38/00;A61K38/05;A61K45/06;A61P31/14;C07D207/12;C07D207/16;C07D241/24;C07D401/12;C07D401/14;C07D403/12;C07D403/14;C07K5/02;C07K5/06;C07K5/10;C07K7/02 主分类号 A61K31/4178
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