发明名称 |
METHOD FOR TREATING CONGESTIVE HEART FAILURE |
摘要 |
<P>PROBLEM TO BE SOLVED: To prevent congestive heart failure by inhibiting the loss of cardiac function, and ideally by improving the cardiac function of those who have congestive heart failure or the risk thereof. <P>SOLUTION: The present invention features a method for treating or preventing congestive heart failure by administering a polypeptide containing an epidermal growth factor encoded by a neuregulin gene. The method is a method for treating or preventing the congestive heart failure in a mammal including a step of administering a polypeptide containing an epidermal growth factor-like (EGF-like) domain to the mammal, wherein the EGF-like domain is encoded by a neuregulin gene, and wherein the administration step includes administering an effective amount for treating or preventing the heart failure in the mammal. <P>COPYRIGHT: (C)2011,JPO&INPIT |
申请公布号 |
JP2011157402(A) |
申请公布日期 |
2011.08.18 |
申请号 |
JP20110116364 |
申请日期 |
2011.05.24 |
申请人 |
CENES PHARMACEUTICALS INC;BRIGHAM & WOMEN'S HOSPITAL INC;BETH ISRAEL DEACONESS MEDICAL CENTER |
发明人 |
MARCHIONNI MARK;KELLY RALPH;LORELL BEVERLY;SAWYER DOUGLAS B |
分类号 |
A61K38/22;C12N15/09;A61K38/00;A61K38/18;A61K39/395;A61K48/00;A61P9/00;A61P9/04;A61P43/00 |
主分类号 |
A61K38/22 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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