发明名称 METHOD FOR TREATING CONGESTIVE HEART FAILURE
摘要 <P>PROBLEM TO BE SOLVED: To prevent congestive heart failure by inhibiting the loss of cardiac function, and ideally by improving the cardiac function of those who have congestive heart failure or the risk thereof. <P>SOLUTION: The present invention features a method for treating or preventing congestive heart failure by administering a polypeptide containing an epidermal growth factor encoded by a neuregulin gene. The method is a method for treating or preventing the congestive heart failure in a mammal including a step of administering a polypeptide containing an epidermal growth factor-like (EGF-like) domain to the mammal, wherein the EGF-like domain is encoded by a neuregulin gene, and wherein the administration step includes administering an effective amount for treating or preventing the heart failure in the mammal. <P>COPYRIGHT: (C)2011,JPO&INPIT
申请公布号 JP2011157402(A) 申请公布日期 2011.08.18
申请号 JP20110116364 申请日期 2011.05.24
申请人 CENES PHARMACEUTICALS INC;BRIGHAM & WOMEN'S HOSPITAL INC;BETH ISRAEL DEACONESS MEDICAL CENTER 发明人 MARCHIONNI MARK;KELLY RALPH;LORELL BEVERLY;SAWYER DOUGLAS B
分类号 A61K38/22;C12N15/09;A61K38/00;A61K38/18;A61K39/395;A61K48/00;A61P9/00;A61P9/04;A61P43/00 主分类号 A61K38/22
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