发明名称 COMPLEX PROFILE OF CELL ANTIGEN AND TARGET SIGNALING PROTEIN FOR ANALYSIS AND CLINICAL MANAGEMENT OF BLOOD CANCER
摘要 <P>PROBLEM TO BE SOLVED: To provide a method of preparing a complex marker profile of a sample derived of individuals with a suspected neoplastic pathological condition. <P>SOLUTION: A complex marker profile according to the invention enables to identify a subgroup of a neoplastic pathological condition and to predict a clinic course of individuals related to a prognosis and treatment. This method provides a useful tool for selecting a treatment for individuals suffered from the neoplastic pathological condition, including a method of determining a risk group, a method of predicting an increased risk of recurrence, a method of predicting an increased risk of development of second complication, a method of selecting of treatment for individuals, a method of determining a treatment effect of individuals, and a method of determining prognosis of individuals. In particular, this method discloses a method of preparing the complex marker profile which plays a role as prognosis indicators for predicting whether a course of the neoplastic pathological condition of individuals is progressive or indolent, resulting in being useful for managing patients and evaluating treatments to be used by clinicians. <P>COPYRIGHT: (C)2012,JPO&INPIT
申请公布号 JP2011221039(A) 申请公布日期 2011.11.04
申请号 JP20110159406 申请日期 2011.07.20
申请人 BECKMAN COULTER INC;NORTHWESTERN UNIV;UNIVERSITY HEALTH NETWORK;CASE WESTERN RESERVE UNIV;ALLEGHENY SINGER RESEARCH INSTITUTE 发明人 CHARLES GOOLSBEE;VINCENT T SHANKEY;DAVID HEDLEY;JAMES JACOBERGER;STANLEY SAKUNI
分类号 G01N33/574;G01N33/53 主分类号 G01N33/574
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