INHIBITOR OF SERINE PROTEASE, PARTICULARLY HCV NS3-NS4A PROTEASE

摘要

PROBLEM TO BE SOLVED: To provide effective anti-HCV therapies.

SOLUTION: The invention relates to compounds represented by formula I or pharmaceutically acceptable salts or mixtures thereof that inhibit serine protease activity, particularly the activity of hepatitis C virus NS3-NS4A protease. As such, they act by interfering with the life cycle of the hepatitis C virus and are also useful as antiviral agents. The invention further relates to compositions comprising these compounds either for ex vivo use or for administration to a patient suffering from HCV infection and to processes for preparing the compounds. The invention also relates to methods of treating HCV infection in a patient by administering compositions comprising the compounds. The invention further relates to processes for preparing these compounds.

COPYRIGHT: (C)2012,JPO&INPIT