EPITOPE IN FISH NODAVIRUS PROTEIN AND A RECOMBINANT VACCINE USING THE SAME

摘要

PURPOSE: A polypeptide containing an epitope of fish nodavirus protein is provided to quickly diagnose fish nodavirus disease. CONSTITUTION: A polypeptide of an epitope of fish nodavirus protein contains an amino acid selected from sequence numbers 1-3. A recombinant expression vector contains the polypeptide. A vaccine composition contains the epitope. The vaccine includes a live vaccine, attenuated vaccine, or killed vaccine. A cell inactivated vaccine is a Streptococcus inactivated vaccine. A method for diagnosing fish nodavirus disease comprises a step of reacting an antibody which specifically recognizes the epitope and a sample containing the fish nodavirus; and a step of determining a sample having positive response to the antibody is infected by the fish nodavirus.