发明名称 |
USE OF ANTI-PROLACTIN AGENT TO TREAT PROLIFERATIVE CONDITION |
摘要 |
<P>PROBLEM TO BE SOLVED: To provide methods and compositions for inhibiting cell proliferation promoting action of prolactin acting at a prolactin receptor, which can be used for treating benign diseases as well malignant diseases involving unwanted cell proliferation. <P>SOLUTION: The invention relates to a therapeutic agent for cancers in humans and proliferative diseases including both benign and malignant diseases of breast and prostate diseases of the breast and prostate caused by a human prolactin variant which acts as an antagonist at the prolactin receptor, and a combination therapy by the administration of anti-estrogens and anti-androgens. <P>COPYRIGHT: (C)2012,JPO&INPIT |
申请公布号 |
JP2012020996(A) |
申请公布日期 |
2012.02.02 |
申请号 |
JP20110149371 |
申请日期 |
2011.07.05 |
申请人 |
ONCOLIX INC |
发明人 |
CHEN WEN Y;WAGNER THOMAS E |
分类号 |
A61K38/22;A61K31/138;A61K38/00;A61K45/00;A61P13/08;A61P15/00;A61P35/00;A61P43/00;C07K14/575;C07K14/705;C07K14/72;C12N5/09;C12N15/09;C12Q1/02 |
主分类号 |
A61K38/22 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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