发明名称 CYCLOHEXYL SUBSTITUTED PYRROLIDINONES AS INHIBITORS OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE 1
摘要 <p>The present invention discloses novel compounds of Formula I: having 11β-HSD type 1 antagonist activity, as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising compounds of Formula I, as well as methods of using the compounds and compositions to treat diabetes, hyperglycemia, obesity, hypertension, hyperlipidemia, metabolic syndrome, and other conditions associated with 11β-HSD type 1 activity.</p>
申请公布号 SI2049475(T1) 申请公布日期 2012.04.30
申请号 SI20070030873T 申请日期 2007.04.24
申请人 ELI LILLY AND COMPANY 发明人 KRASUTSKY ALEXEI PAVLOVYCH;SNYDER NANCY JUNE;WALLACE OWEN BRENDAN;XU YANPING;YORK JEREMY SCHULENBURG
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