| 发明名称 |
OLIGOPEPTIDE RELATED TO MHC CLASS I RELATED TO MELANOMA, AND USE OF THE SAME |
| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide a novel amino acid sequence of an immunogenic peptide that can binds with a human major histocompatibility complex (MHC) class I molecule, and to provide these melanoma-related oligopeptides in a cancer therapy. <P>SOLUTION: The specific melanoma-related oligopeptide induces the melting and the apoptosis of the tumor cell that is recognized as a peptide antigen by a CD8 positive cell cytotoxicity T lymphocyte (CTL), and induced to the CTL. <P>COPYRIGHT: (C)2012,JPO&INPIT |
| 申请公布号 |
JP2012180359(A) |
申请公布日期 |
2012.09.20 |
| 申请号 |
JP20120097324 |
申请日期 |
2012.04.23 |
| 申请人 |
JOHANNES GUTENBERG UNIV MAINZ |
发明人 |
EBERTS DANIELA;FATHO MARTINA;LENNERZ VOLKER;SCHMID CHRIS;VAN DER BRUGGEN PIERRE;WOELFEL CATHERINE;WOELFEL THOMAS |
| 分类号 |
A61K39/00;A61K38/00;A61K39/395;A61K48/00;A61P35/00;C07K7/02;C07K7/06;C07K16/00;C07K19/00;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/09 |
主分类号 |
A61K39/00 |
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