摘要 |
<P>PROBLEM TO BE SOLVED: To provide a nicotine-containing patch preparation which enables to suppress degradation of nicotine and discoloration of the patch preparation. <P>SOLUTION: The patch preparation includes a support and an adhesive layer on its at least one surface, wherein the adhesive layer comprises an adhesive polymer, nicotine and a stabilizer, and the stabilizer is at least one kind selected from the group consisting of butylhydroxyanisole (BHA), propyl gallate (PGA), dibutylhydroxytoluene (BHT) and 2-mercaptobenzimidazole (MBI). <P>COPYRIGHT: (C)2013,JPO&INPIT |