| 发明名称 |
FRAMMENTO ANTICORPALE DELLA REGIONE VARIABILE A SINGOLA CATENA (SCFV) IN GRADO DI RICONOSCERE E LEGARE LA PROTEINA UMANA CD99. |
| 摘要 |
<p>The present invention relates to a single-chain variable fragment (scFv) able to recognize an epitope of the extracellular domain of CD99 human protein. The single-chain variable fragment is able to recognize and specifically and selectively bind the epitope of the extracellular domain of CD99 human protein expressed on Ewing sarcoma cells. The fragment can thus be used for the diagnosis and 10 treatment of Ewing sarcoma.</p> |
| 申请公布号 |
IT1397621(B1) |
申请公布日期 |
2013.01.18 |
| 申请号 |
IT2009MI01994 |
申请日期 |
2009.11.13 |
| 申请人 |
ISTITUTO ORTOPEDICO RIZZOLI;ISTITUTO SUPERIORE DI SANITA' |
发明人 |
GELLINI MARA;MALLANO ALESSANDRA;FLEGO MICHELA;PICCI PIERO;DUPUIS MARIA LUISA;CIANFRIGLIA MAURIZIO;ASCIONE ALESSANDRO;SCOTLANDI KATIA |
| 分类号 |
C07K16/28 |
主分类号 |
C07K16/28 |
| 代理机构 |
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代理人 |
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| 主权项 |
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