摘要 |
<P>PROBLEM TO BE SOLVED: To provide a skin model for evaluating skin stimulation which can be conveniently prepared and stably supplied, and in which quantitative evaluation can be performed. <P>SOLUTION: There are disclosed an in vitro skin model composition for evaluating skin stimulation comprising a planar keratinocyte culture material area, and a nerve cell culture material area in which nerve cells are planarly disseminated so as to adjoin non-contactly and at regular intervals to the border of the planar keratinocyte culture material area, wherein the nerve cells proceed into the keratinocyte culture material area by extending axons thereof, a preparation method thereof, and an evaluation method using the same. <P>COPYRIGHT: (C)2013,JPO&INPIT |