| 发明名称 |
INDOLE INHIBITORS OF CRAC |
| 摘要 |
Disclosed are compounds of Formula (I): useful for treatment of autoimmune and inflammatory diseases associated with IL-2 inhibition via modulation of calcium release-activated calcium (CRAC) channels. Also disclosed are methods of making and using the compounds for treatment of diseases associated with CRAC channels.
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| 申请公布号 |
US2013109720(A1) |
申请公布日期 |
2013.05.02 |
| 申请号 |
US201213656830 |
申请日期 |
2012.10.22 |
| 申请人 |
HOFFMANN-LA ROCHE INC.;HOFFMANN-LA ROCHE INC. |
发明人 |
ALAM MUZAFFAR;DUBOIS DAISY JOE;HAWLEY RONALD CHARLES;KENNEDY-SMITH JOSHUA;MINATTI ANA ELENA;PALMER WYLIE SOLANG;SILVA TANIA;THAKKAR KSHITIJ CHHABILBHAI;WILHELM ROBERT STEPHEN |
| 分类号 |
C07D401/14;A61K31/444;A61P9/02;A61P11/00 |
主分类号 |
C07D401/14 |
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