发明名称 |
METHOD FOR TREATING NEURODEGENERATIVE TAUOPATHY |
摘要 |
The present invention is directed to a filamentous bacteriophage for use in treating a neurodegenerative tauopathy or susceptibility to a neurodegenerative tauopathy and a method of using the bacteriophage for reducing the formation of fibrils of tau protein or for disaggregating pre-formed fibrils of tau protein, such as in a patient suffering from neurodegenerative tauopathy. The filamentous bacteriophage used in the present invention does not display (i) a mammalian cell internalization signal (ii) aβ-amyloid antigen or an antibody toβ-amyloid, or (iii) a tau protein antigen or an antibody to tau protein. |
申请公布号 |
KR20140051840(A) |
申请公布日期 |
2014.05.02 |
申请号 |
KR20137023853 |
申请日期 |
2012.03.12 |
申请人 |
RAMOT AT TEL-AVIV UNIVERSITY LTD. |
发明人 |
SOLOMON BEKA |
分类号 |
A61K35/76;A61K39/395;A61P25/00;A61P25/28 |
主分类号 |
A61K35/76 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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