| 摘要 |
PROBLEM TO BE SOLVED: To provide cholesteryl ester transfer protein inhibitors, pharmaceutical compositions containing the inhibitors, and to provide use of the inhibitors to elevate certain plasma lipid levels, including high density lipoprotein (HDL)-cholesterol and to lower certain other plasma lipid levels, such as low density lipoprotein (LDL)-cholesterol and triglycerides, thereby to treat diseases that are affected by low levels of HDL cholesterol and/or high levels of LDL-cholesterol and triglycerides, such as atherosclerosis and cardiovascular diseases in certain mammals including humans.SOLUTION: Provided are cholesteryl ester transfer protein(CETP) inhibitors of the formula (Ia) and (Ib), and pharmaceutical compositions containing the inhibitors. |
