Molecular Imaging of Cancer Cells In Vivo

摘要

Cellular targets on cancer cells have been identified that can be used with targeted molecular imaging to detect the cancer cells in vivo. Non-invasive methods for detecting cancer cells, such as metastasized cancer cells, are therefore provided. Also provided are compositions and kits for use in the disclosed methods.

主权项

1. A non-invasive method for in vivo detection of cancer cells in a subject, the method comprising:
administering to the subject a targeted imaging probe that specifically binds a cellular target, wherein the cellular target is Toll-like Receptor 2 (TLR2); and imaging the subject with a molecular imaging device to detect the targeted imaging probe in the subject, wherein detection of the targeted imaging probe in an organ of a subject is an indication of cancer cells in the organ.