发明名称 Solid Forms of (R)-1(2,2-Difluorobenzo[D][1,3]Dioxol-5-yl)-N-(1-(2,3-Dihydroxypropyl-6-Fluoro-2-(1-Hydroxy-2-Methylpropan-2-yl)-1H-lndol-5-yl)-Cyclopropanecarboxamide
摘要 The present invention relates to solid forms of (R)-1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)-N-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl)cyclopropanecarboxamide (Compound 1) in substantially crystalline form (Form A) or amorphous form, pharmaceutical compositions thereof, and methods of treatment therewith.
申请公布号 US2015005344(A1) 申请公布日期 2015.01.01
申请号 US201414318131 申请日期 2014.06.27
申请人 Vertex Pharmaceuticals Incorporated 发明人 Keshavarz-Shokri Ali;Zhang Beili;Alcacio Tim Edward;Lee Elaine Chungmin;Zhang Yuegang;Krawiec Mariusz
分类号 C07D405/12;A61K45/06;A61K31/47;A61K31/404 主分类号 C07D405/12
代理机构 代理人
主权项
地址 Boston MA US