| 发明名称 |
FERMENTATION PROCESS |
| 摘要 |
A process for fermenting Bordetella species comprising incubating a sample of bacteria of a Bordetella species in a first environment under at least one bvg (Bordetella virulence genes) modulating condition, for at least 5 generations, to produce a mature culture, and then incubating the mature culture in a second environment in the absence of the at least one bvg modulating condition. |
| 申请公布号 |
US2015010948(A1) |
申请公布日期 |
2015.01.08 |
| 申请号 |
US201314376274 |
申请日期 |
2013.01.30 |
| 申请人 |
GlaxoSmithKline Biologicals S.A. |
发明人 |
Dehottay Philippe Marc Helene;Goffin Philippe |
| 分类号 |
C07K14/235 |
主分类号 |
C07K14/235 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A fermentation process comprising the following steps:
a) providing a sample of bacteria of a Bordetella species; b) incubating the sample of bacteria of a Bordetella species in a first environment under at least one bvg (bordetella virulence genes) modulating condition for at least 5 generations, thereby producing a mature culture; c) incubating the mature culture in a second environment in the absence of the at least one bvg modulating condition; wherein step c) occurs after step b). |
| 地址 |
Rixensart BE |
