| 发明名称 |
SMOOTH MUSCLE CELL CONSTRUCTS |
| 摘要 |
The present invention relates to the regeneration, reconstruction, augmentation or replacement of luminal organs or tissue structures in a subject in need using scaffolds seeded with autologous or non-autologous cell populations that are or are not derived from the corresponding organ or tissue structure that is the subject of the regeneration, reconstruction, augmentation or replacement. |
| 申请公布号 |
US2015030657(A1) |
申请公布日期 |
2015.01.29 |
| 申请号 |
US201113696051 |
申请日期 |
2011.05.03 |
| 申请人 |
Ludlow John W.;Jayo Manuel J.;Basu Joydeep;Bertram Timothy A.;Genheimer Christopher W.;Guthrie Kelly I.;Ilagan Roger M.;Jain Deepak;Knight Oluwatoyin A.;Payne Richard;Quinlan Sarah F.;Rapoport H. Scott;Sangha Namrata D.;Shokes Jacob E.;Burnette Teresa B.;Boyd Sarah A.;Halberstadt Craig R.;Justewicz Dominic M.;Rivera Elias A.;Sharp Wendy;Robbins Neil F. |
发明人 |
Ludlow John W.;Jayo Manuel J.;Basu Joydeep;Bertram Timothy A.;Genheimer Christopher W.;Guthrie Kelly I.;Ilagan Roger M.;Jain Deepak;Knight Oluwatoyin A.;Payne Richard;Quinlan Sarah F.;Rapoport H. Scott;Sangha Namrata D.;Shokes Jacob E.;Burnette Teresa B.;Boyd Sarah A.;Halberstadt Craig R.;Justewicz Dominic M.;Rivera Elias A.;Sharp Wendy;Robbins Neil F. |
| 分类号 |
A61K35/34 |
主分类号 |
A61K35/34 |
| 代理机构 |
|
代理人 |
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| 主权项 |
1. An implantable cell-scaffold construct for treating a subject in need comprising
a) a scaffold comprising a matrix having a first surface, wherein the matrix is shaped to conform to at least a part of a native luminal organ or tissue structure in the subject; and b) a first cell population derived from a source that is non-autologous to the subject and is not the native organ or tissue structure deposited on or in the first surface, said scaffold and said first cell population forming an implantable construct. |
| 地址 |
Carrboro NC US |
