HYDROPHILIC GEL MATERIALS AND METHODS OF MAKING

摘要

The present disclosure describes articles, such as medical articles, containing a substrate having disposed thereon a hydrophilic gel material (e.g., a shaped hydrophilic gel material or a coating of a hydrophilic gel material) and methods for making such articles. Methods are provided for making hydrophilic gel materials from a precursor composition that contains a polar solvent and a polymerizable material that is miscible with the polar solvent.

主权项

1. A method of making an article comprising a substrate and a hydrophilic gel material adhered thereto, the method comprising:
providing a precursor composition comprising:
(a) at least 10 weight percent polar solvent based on a total weight of the precursor composition; and(b) polymerizable material capable of free-radical polymerization and having an average number of ethylenically unsaturated groups per molecule equal to at least 1.2, wherein the polymerizable material is miscible with the polar solvent; providing a mold having at least two separate wells; adding the precursor composition to the mold, the precursor composition being positioned in at least a portion of at least two separate wells; providing a substrate and positioning the substrate to at least partially contact the precursor composition; and exposing the precursor composition within the wells to radiation to at least partially polymerize the polymerizable material and to form a first swollen shaped hydrophilic gel material adhered to the substrate.