| 发明名称 |
PYRIMIDINE-PYRIDINONE SERINE/THREONINE KINASE INHIBITORS |
| 摘要 |
<p>Compounds having the formula (I) wherein R1, R2, R3, R4, R5, Ra, Rb, Rc, Rd, Re, n, r, s and t are as defined herein and which compounds are inhibitors of PAKl. Also disclosed are compositions and methods for treating cancer and hyperproliferative disorders.</p> |
| 申请公布号 |
WO2015011252(A1) |
申请公布日期 |
2015.01.29 |
| 申请号 |
WO2014EP66000 |
申请日期 |
2014.07.25 |
| 申请人 |
F. HOFFMANN-LA ROCHE AG;GENENTECH, INC. |
发明人 |
CRAWFORD, JAMES JOHN;DROBNICK, JOY;GAZZARD, LEWIS J.;LEE, WENDY;NDUBAKU, CHUDI;RUDOLPH, JOACHIM |
| 分类号 |
C07D471/04;A61K31/519;A61P35/00;C07D491/107;C07D491/113 |
主分类号 |
C07D471/04 |
| 代理机构 |
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