| 摘要 |
<p>PROBLEM TO BE SOLVED: To solve the problems in the production of a Grignard reagent by using an alkyl iodide compound and magnesium.SOLUTION: There is provided a method for producing a Grignard reagent represented by the following formula (2), RMgI (2) by reacting an alkyl iodide compound represented by the following formula (1), RI (1) (where, R represents a methyl group or an ethyl group) and magnesium in 4-methyltetrahydropyran. According to the present invention, a Grignard reagent can be easily produced, the cost of apparatus and equipment can be reduced and the reaction operation in the subsequent process can be simplified. Further, since 4-methyltetrahydropyran as a solvent can be reused, the amount used of the solvent can be reduced.</p> |
