Seamless Tubular Extracellular Matrix Prosthetic Valve and Method for Forming Same

摘要

A seamless prosthetic valve having an outer abluminal surface, a triple walled intermediate portion, and at least one valve leaflet that is configured to selectively restrict fluid flow through the valve, the valve leaflet being formed by suturing the triple walled intermediate portion at a first commissure connection point.

主权项

1. A seamless prosthetic valve, comprising:
a continuous tubular structure having an inner lumen, outer abluminal surface, first and second ends, a triple walled intermediate portion, and first and second valve leaflets, said tubular structure comprising extracellular matrix (ECM) from a mammalian tissue source, said first and second valve leaflets being configured to transition from a first position, wherein fluid flow in a first direction through said seamless prosthetic valve is unrestricted, to a second position, wherein fluid flow in a second direction through said seamless prosthetic valve is restricted, said triple walled intermediate portion being formed by everting said first end of said tubular structure over said tubular structure to form a double walled first end and a doubled wall portion proximal to and extending from said double walled end, and reverting said first end of said tubular structure over said double walled end of said tubular structure, said first and second valve leaflets being formed in said tubular structure lumen by suturing said triple walled intermediate portion at two commissure connection points, wherein said first and second valve leaflets comprise two restrained regions and two unrestrained regions.